Long-haul flights get blamed for jet lag and crumpled necks, but the physical toll starts far earlier than the arrival gate. Dr. Laleh Gharahbaghian, a clinical professor of emergency medicine at Stanford School of Medicine, walked Sunset through the cascade of changes your body goes through between takeoff and touchdown — and some of it is worth taking seriously.

The pressure shifts hit first. As the cabin pressurizes and depressurizes during ascent and descent, your ears and lungs feel it. If you're congested, that blocked ear pain on landing is your body protesting — and in rare cases, an already weakened lung can collapse further under the change. Once you're cruising, the lower oxygen absorption in the cabin usually isn't dangerous, but it can leave you unusually tired. Add a time-zone jump scrambling your circadian rhythm and you get the familiar brain fog that makes day one of a trip feel like wading through mud. Stiff joints and dehydration, thanks to the desert-dry cabin air, round out the standard package.

The serious item on the list is blood. Sitting for hours lets gravity pool blood in your legs and feet, which raises the risk of deep vein thrombosis — clots that can travel to the lungs and cause a life-threatening pulmonary embolism. Anyone can develop them on a long flight, but the risk is higher if you're pregnant or postpartum, on hormone therapy or birth control, being treated for cancer, or recovering from major surgery.

The good news: the fixes are simple and cheap. Compression socks help, and so does moving — walk the aisle every couple of hours, or do calf raises near the galley when you get up. Hydration matters more than most people think; skip the coffee and wine, which are both dehydrating, and stick to water. If you're flying with a cold, take a decongestant at the gate before pressure changes start. And sleep when you can, ideally in line with your destination's time zone — an eye mask earns its place in the carry-on.

This is worth knowing whether you're doing the West Coast-to-Europe schlep or a shorter hop to Hawaii. None of the advice requires a medical degree or a first-class seat — just a pair of compression socks, a water bottle, and the discipline to get up between in-flight movies. Frequent flyers and anyone in a higher-risk group should treat it less as trivia and more as a pre-flight checklist.