You arrive at a beautiful bush lodge after a six-hour drive, sink into crisp linen, and then lie wide awake at 2am listening to every distant animal call. Sound familiar? It's not the lodge's fault — and it's not yours either. Sleep researchers have a name for it: the first-night effect.

A Brown University study found that on a first night somewhere new, one hemisphere of the brain (the left) stays partially alert during deep sleep, like a sentry keeping watch. Tones played into the ear feeding that hemisphere woke people more easily, and the difference vanished by night two. The explanation is evolutionary: lighter sleep in unfamiliar surroundings helped our ancestors spot danger. Your four-star suite with a locked door doesn't register with that ancient system.

Travel days pile on more problems. Caffeine lingers in the body for up to eight hours, so that 3pm roadside flat white is still working at bedtime. Alcohol is sneakier — a sundowner feels sedating, but as it wears off it has an alerting effect that jolts you awake in the second half of the night. Experts suggest skipping drinks four to six hours before bed, which on holiday feels like a tall order but is really a trade: one less drink for one better night.

Heading somewhere high, like the Drakensberg or the Lesotho highlands? Altitude adds its own problems. Low oxygen and periodic breathing — waves of breath that sometimes end in a gasp — mean more awakenings and less deep and REM sleep. It eases with a week or more of acclimatisation, so build a gradual climb into your itinerary rather than driving straight to the highest point and sleeping there on night one.

There's a practical kit that helps. Pack an eye mask and earplugs, your own pillowcase (familiar smells signal safety), a downloaded white-noise playlist since remote areas often have patchy signal, a small headlamp for night-time bathroom trips, and a water bottle. Sleep specialist Dr Cheri Mah of Stanford recommends bringing familiar items from home, and keeping a short wind-down ritual — stretching, reading, tea — even on holiday.

Daylight is your best free tool: roughly 30 minutes outside in the morning helps reset your body clock, so take your coffee onto the stoep instead of drinking it in the car. If you're flying across several time zones, expect roughly one day of jet lag per hour of time difference; melatonin isn't recommended for jet lag due to thin evidence.

The kindest move is adjusting expectations. A rough first night is normal, so don't schedule your biggest drive or hardest hike for the morning after arrival — give yourself a day to settle. And if bad sleep persists for weeks at home, or you wake gasping, that's worth mentioning to a doctor. Poor sleep plus headache and nausea at altitude can signal acute mountain sickness: rest, descend if it worsens, and don't climb higher.

The best night of any trip, as the saying goes, is the second one — when your brain finally decides it's safe to switch off.